37signals is dropping support for IE6:

The Internet Explorer 6 browser was released back in 2001, and Internet Explorer 7, the replacement, was released nearly two years ago in 2006. Modern web browsers such as IE 7, Firefox, and Safari provide significantly better online experiences. Since IE 6 usage has finally dipped below a small minority threshold of our customers, it’s time to finally move beyond IE 6.

May this be the first in a long-line of similar announcements.